Pathophysiology
Clinical meaning
NPWT applies sub-atmospheric pressure to the wound bed. This removes exudate/infectious material, reduces edema, and creates 'microstrain' on cells which stimulates mitosis, angiogenesis (new blood vessels), and granulation tissue formation. Connect Negative Pressure Wound Therapy to bedside cues you will reassess first: vitals trends, work of breathing, perfusion, mentation, and pain or ischemic equivalents when relevant. Boards reward recognizing when subtle instability outweighs reassurance, then selecting nursing actions that protect airway, circulation, and neurologic status before routine tasks.