Pathophysiology
Clinical meaning
Advanced 12-lead ECG interpretation requires understanding the cardiac conduction system at the cellular level and correlating electrical patterns with anatomical regions of the heart. Cardiac Conduction Pathway: SA Node (intrinsic rate 60-100) โ Atrial depolarization (P wave) โ AV Node (0.12-0.20 sec delay = PR interval) โ Bundle of His โ Right and Left Bundle Branches โ Purkinje Fibers โ Ventricular depolarization (QRS complex, <0.12 sec) โ Ventricular repolarization (T wave) 12-Lead Anatomical Correlation: โข Inferior: Leads II, III, aVF โ Right Coronary Artery (RCA) territory โข Anterior: Leads V1-V4 โ Left Anterior Descending (LAD) territory (the 'widow maker') โข Lateral: Leads I, aVL, V5-V6 โ Left Circumflex (LCx) territory โข Septal: Leads V1-V2 โ LAD septal perforators โข Right Ventricular: V4R โ RCA proximal โข Posterior: Reciprocal changes in V1-V3 (ST depression, tall R waves) Systematic ECG Interpretation (12-Step Method): 1. Rate: Calculate (300 รท number of large boxes between R-R) 2. Rhythm: Regular or irregular? P waves present and consistent? 3. P Waves: Shape, direction, one P per QRS? 4. PR Interval: 0.12-0.20 sec (3-5 small boxes). Prolonged...
