Key Concepts
Introduction
Adult–Gerontology primary care NP (deepest track here) AGPCNP items expect you to hold multiple chronic problems in working memory: HF + CKD + AF + OA + insomnia in one vignette, then choose the next medication change that reduces harm without abandoning evidence-based therapy that still matches goals. Frailty and life expectancy When stems flag recurrent falls, slow gait, dependence, or limited reserve, tight chronic targets (A1c, BP) may yield to hypoglycemia prevention, orthostasis reduction, and function preservation—pick answers that individualize, not maximize numbers. Geriatric syndromes as outcomes Tie polypharmacy to falls, delirium, urinary retention, constipation, anorexia, and bleeding—then deprescribe or substitute with monitoring. Collaboration Complex deprescribing may involve cardiology, nephrology, psychiatry, and pharmacy—NP answers show coordinated taper plans and clear handoffs, not silent changes. Expect prioritization: which drug to address first when GI bleed risk, falls, and hyperglycemia coexist. Mechanism questions link anticholinergics to cognition/constipation/urinary retention, sedatives to falls, NSAIDs to renal/bleeding. STOPP/Beers-style traps • New anticholinergic for insomnia in dementia. • NSAID with CKD + warfarin without gastric protection plan. • Long-acting benzo for new anxiety in **high...