A central-line-associated bloodstream infection, or CLABSI, is a serious, largely preventable healthcare-associated infection that occurs when organisms enter the bloodstream by way of a central venous catheter. Because the catheter tip sits in a large central vein, an infection seeds the blood directly, producing sepsis, prolonged stays, and significant mortality. CLABSI prevention rests on two evidence-based bundles, one for insertion and one for maintenance, and the nurse owns most of the maintenance bundle every shift. The central insight is that CLABSI is preventable through reliable, repeated execution of small steps rather than any single dramatic action. Maximal sterile barriers at insertion, meticulous hub disinfection, clean dressings, and daily review of whether the line is still needed together drive infection rates toward zero. Picture the bedside: you are the nurse caring for a client with a tunneled central line who now has a fever, chills, and a tender insertion site. Which action takes priority? You recognize possible CLABSI, assess the site and vital signs, and notify the provider so blood cultures can be drawn from the line and a peripheral site...