Antenatal Corticosteroids: Betamethasone and Dexamethasone For

Antenatal corticosteroids represent one of the most significant advances in perinatal medicine. First demonstrated effective in the 1970s, their administration before anticipated preterm delivery reduces: - Respiratory distress syndrome (RDS) by ~50% - Intraventricular hemorrhage (IVH) by ~40% - Necrotizing enterocolitis (NEC) by ~50% - Overall neonatal mortality in preterm infants This single intervention, costing pennies, has saved hundreds of thousands of premature lives. Understanding administration protocols, timing, and nursing monitoring is essential for the NCLEX and REx-PN. Clinical context: Antenatal steroids are most effective when delivery is anticipated within 7 days, the gestational age is 24+0 to 36+6 weeks, and the complete course is administered. The window of protection is 7 days; benefit wanes after that period.