Mechanical Ventilation Management involves alterations in airway structure, gas exchange, or pulmonary vascular function. Mechanical Ventilation Management pathophysiology includes changes in ventilation-perfusion matching, airway resistance, and pulmonary compliance. Connect Mechanical Ventilation to bedside cues you will reassess first: vitals trends, work of breathing, perfusion, mentation, and pain or ischemic equivalents when relevant. NCLEX items often reward recognizing when subtle instability outweighs reassurance, then selecting nursing actions that protect airway, circulation, and neurologic status before routine tasks.