Renal acid-base disorders arise when failing kidneys cannot excrete acid or regenerate bicarbonate — producing metabolic acidosis with hyperkalemia and possible Kussmaul respirations. Nursing priorities include ABG interpretation, dialysis coordination, and airway support when compensation fails. Connect Renal Acid-Base Disorders to bedside cues you will reassess first: vitals trends, work of breathing, perfusion, mentation, and pain or ischemic equivalents when relevant. NCLEX items often reward recognizing when subtle instability outweighs reassurance, then selecting nursing actions that protect airway, circulation, and neurologic status before routine tasks.