Overview
Introduction
An adult with new haemoptysis, falling haemoglobin, microscopic haematuria, and rising creatinine has a pulmonary–renal emergency until anti GBM disease is excluded.
An adult with new haemoptysis, falling haemoglobin, microscopic haematuria, and rising creatinine has a pulmonary–renal emergency until anti-GBM disease is excluded. The same autoantibody can injure alveolar and glomerular basement membranes, allowing respiratory compromise and irreversible kidney failure to progress together. Escalate urgently: collect definitive tests, involve nephrology and critical care, and prepare treatment on a presumptive diagnosis when organ injury is advancing rather than waiting for a laboratory result.