Clinical Meaning
Chronic Complications of Diabetes are the predictable downstream consequences of sustained hyperglycemia driven microvascular and macrovascular injury.
Chronic Complications of Diabetes are the predictable downstream consequences of sustained hyperglycemia-driven microvascular and macrovascular injury. Retinopathy: fragile new vessel formation → vitreous hemorrhage, traction retinal detachment → blindness. Nurse screens annually (dilated fundus exam). Early: no symptoms — screening is the only protection. Nephropathy: glomerular sclerosis progresses from microalbuminuria → overt proteinuria → declining GFR → CKD → ESRD. Annual urine albumin/creatinine ratio, BP control, ACE inhibitor/ARB therapy per orders. Neuropathy: peripheral (burning/tingling/numbness in stocking-glove distribution), autonomic (gastroparesis, orthostatic hypotension, urinary retention, cardiac denervation), and focal. Foot exam every visit; daily foot inspection teaching. Macrovascular: CAD is the leading cause of death in T2 diabetes. PAD causes claudication and poor wound healing. Stroke risk is 2–4× increased. Boards test: annual complication screening schedules; Charcot foot recognition; non-healing wound as a referral trigger; and teaching that glucose control + blood pressure control + lipid management all independently reduce complication risk.
